Clinical Scientist Associate Director, Cardiovascular

Amgen

Clinical Scientist Associate Director at Amgen overseeing global cardiovascular clinical trials and ensuring high-quality data for regulatory submissions. Collaborating cross-functionally for successful delivery of projects.

Posted 5/27/2026full-timeRemote • 🇺🇸 United StatesSenior💰 $169,793 - $229,721 per yearWebsite

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Hard Skills

clinical developmentclinical trial process improvementscardiovascular medicinedata cleaningdatabase lockdata extractionendpoint validationregulatory submission documentsclinical data reviewsignal detection

Soft Skills

communication skillspresentation skillscollaborationrisk identificationmitigation strategies

Tools & Technologies

Spotfiredata visualization toolsanalysis outputs

Certifications & Qualifications

Good Clinical Practice (GCP)

Industry Keywords

cardiovascular trialsglobal clinical studiesregulatory requirementsclinical protocolssafety monitoringData Monitoring Committee (DMC)clinical study reportsscientific publicationsevent-driven studiestherapeutic area

About the role

Key responsibilities & impact

Supports the design, execution, and oversight of cardiovascular trials and other late-phase global clinical studies.
Contributes to protocol development, study execution, medical monitoring support, and clinical data review, ensuring delivery of high-quality, decision-ready clinical data for regulatory submissions and scientific dissemination.
Support the design, start-up, and execution of global cardiovascular trials, ensuring adherence to protocol, regulatory requirements, and data integrity standards.
Contribute to development of clinical protocols, statistical analysis plans, investigator brochures, and regulatory documents, with particular focus on cardiovascular endpoints and safety outcomes.
Collaborates with cross-functional teams to support endpoint strategy, event adjudication processes, and cardiovascular safety monitoring.
Participates in development and oversight of endpoint adjudication charters, safety monitoring plans, and Data Monitoring Committee (DMC) interactions.
Provides clinical input into data management plans, CRF design, and clinical data review, with focus on cardiovascular outcomes endpoints (e.g. MACE, hospitalization events, mortality) and/or cardiac imaging endpoints.
Conducts ongoing clinical data review and signal detection, supporting identification and resolution of safety and data quality issues across global trial sites.
Supports preparation and interpretation of interim analyses, database lock activities, and top-line data readouts.
Assists Development Lead and Clinical Scientist Director with medical monitoring activities and oversight of CROs, vendors, and adjudication committees.
Collaborates with clinical operations, biostatistics, safety, regulatory, and medical affairs teams to ensure successful delivery of cardiovascular outcomes and/or cardiac imaging studies.
Contributes to clinical study reports, regulatory submissions, scientific publications, and presentations for internal and external stakeholders.
Identifies operational or scientific risks and proactively implement mitigation strategies across cross-functional teams.

Requirements

What you’ll need

Doctorate degree and 3 years of clinical development experience OR Master’s degree and 5 years of clinical development experience OR Bachelor’s degree and 7 years of clinical development experience OR Associate’s degree and 12 years of clinical development experience OR High school diploma / GED and 14 years of clinical development experience
3 years of pharmaceutical clinical drug development experience, including experience supporting late-stage, global clinical trials.
Demonstrated experience contributing to clinical trial process improvements within a therapeutic area or study team environment
Industry or academic experience in cardiovascular medicine and/or cardiovascular outcomes trials; experience in large event-driven studies preferred.
Strong communication and presentation skills, with the ability to clearly convey scientific concepts and clinical data to cross-functional teams and leadership audiences, both written and oral
Experience supporting the design, monitoring, and implementation of clinical trials in compliance with Good Clinical Practice standards and applicable regulatory requirements
Working knowledge of study data readout activities, including data cleaning, database lock, data extraction, endpoint validation, and generation of analysis outputs to support topline and final results.
Experience contributing to regulatory submission documents and supporting clinical regulatory responses for health authority interactions under guidance
Experience serving as a contributing author on scientific publications or data presentations for internal forums or scientific conferences
Experience in clinical data review and analysis tools such as Spotfire, listings review platforms, or other data visualization and analysis tools.

Benefits

Comp & perks

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions
group medical, dental and vision coverage
life and disability insurance
flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible